Supratentorial Gliomas in Eloquent Areas: Which Parameters Can Predict Functional Outcome and Extent of Resection?

Supratentorial Gliomas in Eloquent Areas: Which Parameters Can Predict Functional Outcome and Extent of Resection?

BACKGROUND To date, few parameters have been found that can aid in patient selection and surgical strategy for eloquent area gliomas. AIMS The aim of the study was to analyze preoperative and intraoperative factors that can predict functional outcome and extent of resection in eloquent area tumors. PATIENTS AND METHODS A retrospective analysis was conducted on 60 patients harboring supraten...

Intraoperative neuromonitoring for function-guided resection differs for supratentorial motor eloquent gliomas and metastases

BACKGROUND Recent data show differences in intraoperative neuromonitoring (IOM) in relation to the operated brain lesion. Due to the recently shown infiltrative nature of cerebral metastases, this work investigates the differences of IOM for cerebral metastases and glioma resection concerning sensitivity, specificity, and predictive values when aiming on preservation of motor function. METHOD...

Surgical Treatment of Supratentorial Glioma in Eloquent Areas

Cognitive functioning early after surgery of gliomas in eloquent areas.

OBJECT Patients with gliomas frequently have cognitive deficits, and surgery can exacerbate these deficits. Preoperative assessment is therefore crucial in patients undergoing surgery for glioma in eloquent areas, because the proximity of functional areas increases the risk of permanent postoperative cognitive disturbances. Although pre- and postoperative language and motor function in patients...

Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation.

OBJECTIVES To describe functional recovery after surgical resection of low grade gliomas (LGG) in eloquent brain areas, and discuss the mechanisms of compensation. METHODS Seventy-seven right-handed patients without deficit were operated on for a LGG invading primary and/or secondary sensorimotor and/or language areas, as shown anatomically by pre-operative MRI and intraoperatively by electri...